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Overall, the multimorbidity of depression and T2DM involves shared genetic risk factors and multiple underlying biological mechanisms, including HPA axis dysregulation, pro-inflammatory states, gut-brain axis interactions, and insulin signaling alterations, which can affect neurotransmission

This difference may influence patient and prescriber preferences depending on individual goals and tolerability

Your complete medication list: GLP-1 medications can affect the absorption of oral medications and interact with diabetes medications, insulin, and others

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