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Safety Considerations and Contraindications Who Should Avoid Melanotan II Contraindications : Pregnancy or breastfeeding History of melanoma or skin cancer Severe cardiovascular disease Uncontrolled hypertension Known peptide allergies Drug Interactions for Sexual Health Melanotan II may interact with: Erectile dysfunction medications (may enhance effects) Blood pressure medications Antidepressants (particularly MAOIs) Appetite suppressants Medical Supervision Requirements Consult healthcare providers before starting if you have: Cardiovascular conditions Skin disorders or mole changes Hormonal imbalances Current prescription medications History of psychiatric conditions Our Clinics Experience with Melanotan II for Libido Through extensive clinical experience with Melanotan II for sexual enhancement, weve observed optimal results with 1-1.5 mg daily dosing for most patients