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In a mouse model of bleomycin-induced pulmonary fibrosis, GHK-Cu reduced the inflammatory cytokines TNF- and IL-6 and reduced oxidative stress markers, alongside reversing the disease-associated rise in NF-B and boosting Nrf2

doi: 10.1016/S22138587(22)000857 118 HeiseTDeVriesJHUrvaSLiJPrattEJThomasMKet al

AOD9604 and Safety Pharmacology Research A conventional Ames test showed no significant mutation rate increase for AOD9604 at up to 2,000 g/plate, with no clastogenic effects observed in CHO-cell chromosome aberration assays

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