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Below are the key groups that may benefit from B12 injections: People With Diagnosed Deficiencies Healthcare providers often recommend B12 shots for those with confirmed deficiencies

When used for type 2 diabetes, the dosing recommendations are: Immediate-release tablet: 500 mg once or twice daily, or 850 mg once daily Extended-release tablet: 500 mg1,000 mg once daily For weight loss, PCOS, gestational diabetes, or other off-label uses of metformin, the dosage varies but most people start at 500 mg

No results have been posted to the registry , so the answer for oral drugs taken alongside retatrutide is not yet public