About 54% of adults who had taken a GLP-1 drug, including those with insurance, said the cost was difficult to afford, according to KFF poll results released this month
Notably, only one registered clinical study exists to date, which evaluates an implant-based delivery system of Exenatide and is currently in Phase 1 with an Active, not recruiting status (NCT05670379), initiated on December 20, 2024, and expected to conclude by August 2025
If your prior GLP-1 history has been rough, tirzepatide had slightly fewer GI discontinuations in the only direct tirzepatide vs semaglutide comparison
While semaglutide itself does not cause significant hepatotoxicity, patients with pre-existing liver disease, those who consume 3 or more alcoholic drinks every day, or individuals taking other potentially hepatotoxic medications should consult their healthcare provider before regular acetaminophen use