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In preclinical models, GIP has been shown to decrease food intake and increase energy expenditure therefore resulting in weight reductions, and when combined with GLP-1 receptor agonism, may result in greater effects on markers of metabolic dysregulation such as body weight, glucose and lipids. Incretin hormones are released whenever food is consumed

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Going back to the piece that Alex wrote, he references this idea of the better than the Beatles problem

FDA warning letters Regulator Used to verify enforcement history and avoid unsupported safety claims