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Unlike older compounds in its class, it specifically targets the growth hormone secretagogue receptor without significantly elevating cortisol, prolactin, or ACTH levels during assays

Additionally, long-term data on its effectiveness are limited compared to other procedures

Lack of Long-Term Data: We simply don't have long-term human safety data for most of these peptides

The notion for combining entero-pancreatic hormone-based therapies for obesity treatment is supported by the efficacy of bariatric surgery on WL, an intervention leading to increased postprandial levels of multiple entero-pancreatic hormones [31, 32]