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Patients taking both agents should monitor for signs of hypoglycemia (shakiness, sweating, confusion), particularly if they are also on insulin or sulfonylureas, because GLP-1 medications lower blood glucose and NAD-boosting compounds may theoretically potentiate this effect in susceptible individuals

Yes, it is important to consider not only the effectiveness and potential side effects of the medications, but also the cost and any potential interactions with other medications

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CI, confidence interval