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At the cellular level, activation of beta-2 receptors produces bronchodilation through multiple pathways, most of which involve stimulation of adenylyl cyclase and phosphorylation of target proteins by protein kinase A (PKA)

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Therefore, both the control strain ( pCYC1-GAP1 ) and the modified strain ( pGSH1-GAP1 ) are expected to show comparable levels of Gap1 expression and D-HIS uptake

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