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Because they work through different mechanisms -- GHK-Cu through broad gene modulation and copper-dependent enzymatic activity, Matrixyl through collagen signal mimicry -- they can be combined for synergistic anti-aging benefits

J Cell Biol 187:733747 Stehbens SJ, Paszek M, Pemble H, Ettinger A, Gierke S, Wittmann T (2014) CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover

Regenerative medicine aims to support the bodys own repair and recovery systems

While selective activation of PPAR by fibric acid derivates (fibrates) primarily improves hepatic lipid and cholesterol metabolism 3 , the selective activation of PPAR by thiazolidinediones (TZDs) enhances insulin sensitivity in peripheral tissues such as the adipose tissue, liver and skeletal muscle 4