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Mild side effects can include: Nausea (especially if you take higher doses than recommended) Headaches (particularly if you are sensitive to nicotinic acid or niacin) Flushing or a feeling of warmth and redness in the skin Diarrhea (especially if taken in high doses) Dizziness (especially if prone to dizziness) Serious adverse reactions: Vomiting (more common with IV infusion) Abdominal discomfort (temporary

Pharmaceutical drugs undergo clinical trial phases to establish a therapeutic dose for human use

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