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Seminars Neurosci 6(4):239246 Mndez-Armenta M, Nava-Ruz C, Jurez-Rebollar D, Rodrguez-Martnez E, Gmez PY (2014) Oxidative stress associated with neuronal apoptosis in experimental models of epilepsy
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In conclusion, the study robustly demonstrated that FOXO4-DRI selectively eliminates senescent Leydig cells, reduces detrimental SASP factor secretion, improves the testicular microenvironment, and ultimately enhances sperm quality and spermatogenesis in aged mice, positioning it as a promising therapeutic candidate for age-related male infertility [2]
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