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The natural rationale for off-cycle periods involves several mechanisms

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This theory was proposed after it was discovered that the drug chlorpromazine had antipsychotic properties ( However, antipsychotic drugs tend to alleviate positive symptoms more than negative symptoms ( Metabolism of dopamine has been suggested to be a prominent producer of reactive oxygen species in the brain ( 2 O 2 which when in the presence of iron or oxygen can form the more active hydroxyl radical (