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Children and adolescents with lower insulin requirements Adults taking less than 30 units per injection Patients on insulin pump therapy who occasionally need manual injections Anyone who struggles to read smaller markings on larger syringes Real-world application: Imagine a 7-year-old newly diagnosed with Type 1 diabetes

Cagrilintide 2.4 mg Population: BMI 30, no diabetes Key Results (32 Weeks): Mean Weight Loss: 15.1% with CagriSema (combination) 9.8% with semaglutide 2.4 mg alone 7.7% with cagrilintide 2.4 mg alone Synergy Demonstrated: Combination produced 54% more weight loss than semaglutide alone, 96% more than cagrilintide alone 15% Weight Loss: 53% (CagriSema) vs

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revealed through whole-genome CRISPR activation screening that MBOAT1 and MBOAT2 are novel inhibitors of ferroptosis (88)