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Overall, and in all subgroups of the all semaglutide OW cohort, the total proportion of patients in the obesity classes II and III decreased, while the proportion of patients in the lower weight categories (normal and overweight) increased, reflecting the mean weight loss observed with semaglutide OW (Fig

doi: 10.3389/fpubh.2022.996179

However, both can place stress on the digestive system, and documented ibuprofen and semaglutide interactions show that timing, dose, and individual sensitivity matter

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