demonstrated that AC synergistically enhanced the cytotoxic abilities of 5-FU, caused G1 cell cycle arrest, and promoted apoptosis by modulating the anti-apoptotic B-cell lymphoma 2 (Bcl2) and the pro-apoptotic Bcl-2-associated X protein (Bax), and to a lesser degree, Bcl-xL and p53
Furthermore, GSH supplementation has been shown to protect HIV patients from a variety of opportunistic diseases by (i) mitigating oxidative stress and chronic inflammation in HIV-associated neurodegenerative diseases, (ii) improving Th17 responses in HIV patients who have impaired gut mucosal defenses, and (iii) restoring Th1 responses to protect patients from TB coinfection
Zhejiang: Zhejiang University
Mishra, S., Stierman, B., Gahche, J., & Potischman, N