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Furthermore, the PfGrx-catalyzed oxidation of roGFP2 is more than four orders of magnitude faster than the uncatalyzed reaction with GSSG and occurs two orders of magnitude faster via the glutathione-dependent monothiol mechanism than by the glutathione-independent dithiol mechanism (Fig

The most commonly used drugs are aminosalicylates, corticosteroids (CS), immunomodulators (for example, thiopurines (TPs), methotrexate (MTX), calcineurin inhibitors, Janus kinase (JAK) inhibitors) and biologics drugs

doi: 10.1159/000330447 74 HegedsLShermanSITuttleRMvon ScholtenBJRasmussenSKarsblJDet al