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In another study, the role of MOTS-c in TGF-/Smad pathway-mediated osteogenesis was again validated by silencing TGF- and Smad and observing changes in the expression of downstream osteogenic genes ( 3.2.3 Role of MOTS-c in the synthesis of type I collagen by osteoblasts In addition, MOTS-c has been shown to promote the expression of type I collagen secreted by osteoblasts

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Melanin is the pigment responsible for dark spots, uneven skin tone, and hyperpigmentation

[DOI] [PubMed] [Google Scholar] 39.Duni A., Liakopoulos V., Roumeliotis S., Peschos D., Dounousi E