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A perspective paper, not a trial of fiber for post-discontinuation weight maintenance

Its primary mechanism is AMPK activation through inhibition of the folate cycle, causing accumulation of AICAR (an AMP analog) [1] [2]

JACC 84(17):16151628 Wallner M, Biber ME, Stolfo D, Sinagra G, Benson L, Dahlstrm U et al (2024) Glucagon-like peptide-1 receptor agonists use and associations with outcomes in heart failure and type 2 diabetes: data from the Swedish Heart Failure and Swedish National Diabetes Registries

While the mechanisms differ, the potential outcomes, such as muscle growth, recovery, and potential fat loss, are somewhat similar