Some side effects like headaches, nausea and vomiting are usually most noticeable after the first injection, and can last anywhere from a few days to a few weeks
The broader benefits of GLP-1 therapyincluding improvements in body composition, insulin resistance, cardiovascular risk factors, sleep apnea, and overall metabolic healthcan all positively influence reproductive function. Because infertility, obesity, metabolic syndrome, and low testosterone frequently coexist, treating the underlying metabolic disease may have substantial downstream reproductive benefits
Individual results can vary, and factors such as diet, physical activity, starting weight, and medication adherence all play a role
A 2023 study published in JAMA Ophthalmology examined over 16,000 patients and found a small but statistically significant increased risk of certain retinal complications in those prescribed semaglutide compared to other diabetes medications