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With drugs like semaglutide and tirzepatide now widely used in people with IBD who also have obesity or diabetes and with growing interest in their anti-inflammatory effects we wanted to know whether starting one actually changes the course of the IBD itself

The results of the SURPASS trials demonstrate that tirzepatide yields clinically significant improvements in glycemic control and weight loss when compared with other GLP-1 receptor agonists (semaglutide and dulaglutide), insulin degludec, and insulin glargine

The FDA approved it on April 1, 2026, for adults with obesity or adults who are overweight and have at least one weight-related health condition such as high blood pressure, high cholesterol, or type 2 diabetes

A hiatal hernia occurs when the upper part of the stomach pushes up through the diaphragm and into the chest region