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Indicators of endothelial dysfunction, such as sICAM-1, tPA antigen, and PAI-1 levels and activity, are higher in individuals with Metabolic Syndrome (MetS) (67)

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HT was first described in families with symptoms suggestive of MC mediator release in association with increased TPSAB1 copy numbers

In some embodiments, auris-acceptable gels include, but are not limited to, alginate hydrogels SAF-Gel (ConvaTec, Princeton, N.J.), Duoderm Hydroactive Gel (ConvaTec), Nu-gel (Johnson & Johnson Medical, Arlington, Tex.), Carrasyn(V) Acemannan Hydrogel (Carrington Laboratories, Inc., Irving, Tex.) glycerin gels Elta Hydrogel (Swiss-American Products, Inc., Dallas, Tex.), and K-Y Sterile (Johnson & Johnson)