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aeruginosa T3SS is induced by several conditions including low Ca 2+ and host cell contact through ExsA [[35], [36], [37]], the redox control of T3SS via Vfr could be another layer of modulation where oxidizing condition could dampen T3SS induction

Investigating these genes in greater detail allows researchers to deepen their understanding of the genetic architecture of depression and to identify potential biomarkers for personalized treatment strategies

They can also regulate tumor related immune responses and improve the prognosis of anti-tumor therapy