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In summary, single-cell metabolomics and integrative multiomics offer powerful tools for elucidating how aging and mechanical forces remodel EC metabolic reprogramming

First, DET1 is intrinsically dynamic and adopts conformational states that are stabilized by DDA1 and engagement of the Ube2e2 family

The Danish pharmaceutical company said the 68-week trial showed that CagriSema led to significantly greater weight loss than its individual components or placebo, underscoring its potential as a leading treatment in the burgeoning obesity drug market

developed a multifunctional polyphenol-copper nanozyme that mimics both catalase and superoxide dismutase activity