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Additionally, the kindling model is not well standardized in zebrafish, as the existing studies only exposed the animals to chronic low doses of PTZ and evaluated the seizure behavior just after the exposure

All clinical trials for dementia outcomes identified by our search 42,43,44 had been included in the meta-analyses above

Notably, mice in the RGD-Lip group developed hypothermia after the third dose, whereas mice in the other groups showed no changes in body temperature and otherwise appeared normal, suggesting that the readministration of RGD-Lip induces immune responses (Fig

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