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The two ingredients shouldn't be used simultaneously due to potential destabilization, but they complement each other when used at different times
In keratinocytes, GHK-Cu has been shown to downregulate inflammatory cytokine production in response to challenge including IL-1, TNF-, and IL-6, the inflammatory mediators most associated with the chronic scalp inflammation seen in androgenetic alopecia.4 In fibroblasts, GHK-Cu stimulates collagen and elastin synthesis, supporting the structural matrix that follicles depend on for anchoring and nutrient supply
The rationale for combining these two peptides is rooted in their complementary mechanisms of action
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