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(85), the introduction of endothelial cells with an inflammatory phenotype into the bloodstreams arterial vessels results in the initiation of an inflammatory response, thereby contributing to the advancement of CVD

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pneumoniae remains a significant public health concern, with reports indicating it is responsible for over 1.2 million deaths annually, primarily affecting young children and the elderly ( Furthermore, the increasing antibiotic resistance of this pathogen poses substantial challenges to the treatment of invasive pneumococcal diseases