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Ecotoxicol Environ Saf 248:114333 Zhou X et al (2025) TRIM32 promotes neuronal ferroptosis by enhancing K63-linked ubiquitination and subsequent p62-selective autophagic degradation of GPX4

for instance, drugs designed to modulate brain mitochondria must penetrate the BBB, which can be achieved through nanoparticle conjugation or chemical modification to enhance lipophilicity [19]

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Experimental findings also suggest that NNMT inhibition may enhance stem cell activity and support regenerative responses in skeletal muscle tissue, making it a compound of interest in ongoing biochemical and metabolic research