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The enzyme glutathione reductase (GR) recycles GSSG to GSH while simultaneously oxidizing ?-nicotinamide adenine dinucleotide phosphate (?-NADPH2)

doi: 10.1021/bi401618y 128

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In one randomized controlled trial, the authors [82] investigated 60 patients with severe pre-eclampsia requiring termination of pregnancy and divided them into two groups: the first group received 70 mg silymarin as a single dose, and the second group received 600 mg NAC at 0, 12 and 24 h after delivery