In the process of ferroptosis, Fe2+ can convert lipid peroxide into ROS, and GPX4 converts lipid peroxide into the corresponding alcohol with the help of GSH (19)
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Psychiatry 65 , 154164 (2008)
Rivera-Delgado D, Kantarjian H, Borthakur G, Konopleva M, Kanagal R, Pemmaraju N, Daver N, Dinardo C, Takahashi K, Jabbour E, Montalban-Bravo G, Yilmaz M, Pierce S, Andreeff M , Bhalla K, Garcia-Manero G, Ravandi F, Kadia TM