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& Turner, D
The metabolic mechanism formed by the above metabolites may be involved in the pathogenesis impacted by SLE
One of the hallmarks of incretin drugs in the brain is that they decrease dopamine release but the specific contribution of GIPR signaling alone was unknown
HFD inhibits the transcription of key antioxidant genes by triggering NRF2 translocation into obese mouse Tregs nucleus, causing a rapid decline in HO-1 expression in Tregs, leading to enhanced oxidative stress and possible ferroptosis, and causing an intensification of obesity and inflammatory responses (156) ( Figure 3 )
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
