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This is supported by the discovery that A549 cells demonstrated survival rates of 28% and 43% when exposed to pDNA/polybia-MP1 and polybia-MP1, respectively

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The immunological findings defined CFS as a low-grade inflammatory disease, indicated by enhanced production of cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS), and nuclear factor kappa B (NF-B), dysregulated cytokine levels (increased levels of IL-1, IL-4, IL-5, IL-6, and IL-12 and decreased levels of IL-8, IL-13, and IL-15), autoimmune reactions, oxidative and nitrosative stress, reduced levels of antioxidant markers, mitochondrial dysfunction, increased translocation of Gram-negative bacteria, and altered antiviral response elements (i.e

[DOI] [PMC free article] [PubMed] [Google Scholar] 184.Redwan EM, Abd El-Baky N, Al-Hejin AM, Baeshen MN, Almehdar HA, Elsaway A, Gomaa A-BM, Al-Masaudi SB, Al-Fassi FA, AbuZeid IE