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This reduction was prevented by MG132 (proteasome inhibitor) but not Lys05 (lysosome inhibitor), indicating that SLC7A11 protein is degraded via the ubiquitin-proteasome pathway rather than the lysosomal pathway [47]

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This protective effect extended to other stressors, as glutathione amino acid precursors also shielded cells from blue light-induced ROS production and pollutant-induced ATP depletion, demonstrating a broad-spectrum protective action