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This hormone is produced naturally by the gut and brain and have multiple effects

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Instead, the following signs are often a red flag for celiac disease in adults: Amenorrhea Arthritis Bone or joint pain Canker sores inside the mouth Depression or anxiety Fatigue Itchy skin rash 1 Infertility Liver and biliary tract disorders Osteoporosis or osteopenia Peripheral neuropathy (tingling, numbness, or pain in the hands and feet) Seizures or migraines Unexplained iron-deficiency anemia Whether or not you are experiencing any of these symptoms, it is crucial to undergo celiac disease testing if you have a first-degree relative with the condition, as this puts you at a one in ten risk of developing celiac yourself