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Their amphiphilic nature, characterized by a hydrophobic core and a hydrophilic surface, enables them to carry a wide range of therapeutic agents, making them effective vaccine delivery systems [87]

In contrast to our results, the authors demonstrated an increase in ECAR within the first hour following in vitro LPS addition and interpreted this as indicative of a switch from oxidative phosphorylation to increased glycolysis as part of the M1 macrophage response following LPS stimulation (51)

Radecki DT, Brown LM, Martinez J, Teyler TJ (2005) BDNF protects against stress-induced impairments in spatial learning and memory and LTP

The entire process can be accomplished in 12 steps with an overall yield of 2.6%, and the product is more than 90% pure without preparative chromatography