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Its unique structure means it is able to interact with multiple pathways in the bodys central nervous system, making it an interesting research model for scientists investigating mechanisms of stress, hormonal regulation and sleep

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Besides contributing to the increase of tumour mass, the rewiring of cholesterol and sphingolipids metabolism alters the composition of lipid rafts that play an important role in other hallmarks of cancer such as oncogenic signalling, migration, proliferation, adhesion, invasiveness, metastatic spread, apoptosis evasion [51], vesicular trafficking and drug resistance [52]