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b Estimated using an ANCOVA based on data irrespectively of discontinuation of trial product or initiation of rescue medication adjusted for baseline value, background medication and region

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The functional effects of GLP-1 analogues on human eosinophils appear to be linked to their ability to reduce LPS-induced membrane expression of CD69 and CD11b, along with the synthesis of cytokines like IL-4, IL-8, and IL-13 [129]

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Conclusions : There is a consensus that clinical symptoms need to receive more attention in establishing the diagnosis of B12 deficiency

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