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It's never been approved as medication in the United States

The concept of enhanced lactate production was first described a century ago by the Warburg effect, which revealed that tumor cells rely on anaerobic glycolysis even in the presence of oxygen, providing them with numerous advantages

But medical experts describe the marketplace as a Wild West of unproven, unregulated drugs that could cause serious harm, including infection, allergic reactions or other problems

Initially corresponding beneficial central influence was seen when BPC 157 was given peripherally and a serotonin release in particular brain areas, mostly nigrostriatal, was changed