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A 2024 RAND analysis found that 68% of commercial health plans limit coverage to diabetes or specific BMI thresholds, leaving many weight-management patients underinsured or uninsured for these medications

Total weight loss by week 12 typically ranges from 5% to 8% of starting body weight, depending on the medication and dose

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Therefore, this review will focus on the following aspects: (a) A basic overview of OA and ferroptosis, highlighting the pathological features of OA as well as the discovery, definition, and core regulatory mechanisms of ferroptosis