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Changes in your menstrual cycle Semaglutide may cause irregular periods, spotting, or missed periods

Most patients reach maintenance within 8 to 12 weeks of starting treatment, depending on tolerance and individual metabolic response

As the chosen mass spectrometry is not suitable for determination of -carotene, this carotenoid was determined by HPLC

Phase 2 (Q1 2026) will add additional samples (up to 25,000 patients) and more detailed clinical phenotype data to identify predictive safety and tolerability markers and include further validation and refinement of the efficacy signals including: Phasing of drug therapy and impact on efficacy Prediction of high rebound cohorts Evaluation of potential efficacy in other indications PrecisionLife has developed and validated a world-leading combinatorial analytics platform to identify the drivers underpinning over 60 complex chronic diseases