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Avoid repeated freeze-thaw cycles, which can promote disulfide rearrangement and loss of the cyclic structure
This is because their bodies make less of a key helper for B12 and absorb it less well
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When a source says one is stronger than the other, it is lining up REDEFINE 1s roughly 20.4% at 68 weeks against SURMOUNT-1s roughly 20.9% at 72 weeks two numbers from two different trials, in different populations, over different durations, against different comparators
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