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Furthermore, a recent extensive cohort study involving over 33,000 GLP-1 RA users diagnosed with diabetes over a 9-year period indicated no significant increase in pancreatic cancer risk associated with GLP-1 RA use, as evidenced by an HR of 0.50 compared to basal insulin [60]

Targeting the different biological causes of menstrual disruption are various interesting classes of peptides, including gonadotropin-modulating peptides, insulin-sensitizers, anti-inflammatory peptides, and metabolic peptides which may be combined with lifestyle interventions

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