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Make sure youre getting enough to preserve muscle mass

For example, in the phase 3 SURPASS-1 trial, the investigators deemed that tirzepatide had a safety profile consistent with that of other GLP-1 receptor agonists, while in the phase 3 SURPASS-4 trial, the investigators ruled out excess cardiovascular risk as a safety concern in administering tirzepatide to type 2 diabetes patients [5, 6]

There is also the question of "non-responders." While tirzepatide has a very high success rate in metabolic research, a small percentage of subjects do not reach the desired benchmarks

Efficacy of cumulative high-frequency rTMS on freezing of gait in Parkinsons disease