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Inflammatory Response They modulate inflammatory cytokine profiles in the reproductive tract, downregulating proinflammatory mediators like TNF-, IL-6, and IL-1, and sometimes increasing anti-inflammatory cytokines such as IL-10

Redox regulation of PTPN22 affects the severity of T-cell-dependent autoimmune inflammation

Acknowledgments BioRender was used for the creation of Figure 1

In the brains of Alzheimer's mouse model, genetic deletion of Fpn increased ferroptosis and then induced memory impairment, while restoring Fpn ameliorated ferroptosis and memory impairment ( GSH-dependent Pathway Glutathione peroxidase 4 (GPX4) is a selenium (Se)-containing enzyme, which plays a central role in the reduction of lipid ROS production