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Oxidative stress may then damage mitochondrial membranes and enzymes, further lowering ATP production and increasing the need for glutathione, SOD, catalase and other antioxidant defenses

Important contributors include magnesium , zinc , folates , and vitamins E, B2, B6, and B12

[18] Bleeding in infants due to vitamin K deficiency can be severe, leading to hospitalization, brain damage, and death

Since treatment of obesity as a chronic disease would require long-term AOM use in many individuals, the cost-effectiveness of this approach has yet to be established and such an approach, while clinically recommended, may potentially put a strain on health systems