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The preclinical data suggests the hypothesis that inhibitory GIPR + neurons act specifically on GLP-1R + neurons that drive nausea and food aversion or avoidance to dampen GLP-1R mediated nausea without reducing efficacy, potentially lifting the ceiling of GLP-1R agonist-induced reductions in body weight

Apoptosis and DNA damage mediated by ROS involved in male reproductive toxicity in mice induced by Nickel

Dose-finding RCT of diabetic patients (N = 1210) given either GLP1/GIP medication weekly or PC: After 68 weeks, mean weight loss was 10% ( GLP1/GIP medication ), 7% (lower dose GLP1/GIP medication ), and 3% (PC)

Expanded nutrition guidance to encourage evidence-based eating patterns, including those incorporating plant-based proteins and fiber, that keep nutrient quality, total calories, and metabolic goals in mind