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HbA1c, fasting insulin, lipid panels, thyroid function, and inflammatory markers all tell a story about your metabolic health trajectory that is independent of scale weight

Mitochondrial dynamics shift, affecting fission-fusion balance and uncoupling protein expression[9]

Most academic obesity medicine programs teach that GLP-1 monotherapy should be maximized first, and only if weight loss plateaus despite adequate dosing should additional agents be consideredalways under close specialist supervision

SURMOUNT-4) Recognizing what happens to your body weight after stopping GLP-1s is crucial for setting realistic expectations