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One review of the biological activities of Opuntia ficus-indica (the scientific name for cactus fruit) polysaccharides noted their "ideal" anti-inflammatory effects and other therapeutic properties

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Doses exceeding approximately 100 mg of oral morphine equivalent may be more likely to trigger the onset of OPIAD, compared with lower opioid doses [73], although this finding has not been confirmed by other researchers [56, 65]

The disruption leads to iron accumulation, which in turn intensifies lipid peroxidation and causes ferroptosis (54)