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While huntingtin folds and functions normally, the mutant form exhibits aberrant folding, leading to aggregation and neuronal toxicity

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Salivary glutathione levels, evidence of the neutralization (scavenging) of ROS were low in patients from periodontal diseases in contrast to individuals with healthy gums.[111] Studies have demonstrated reduced amounts of salivary glutathione, GSH peroxides and thiol levels in the gingivitis and periodontitis patients as compared to the healthy group [Table 3].[72,107,111] Table 3