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Dina Peralta Hi Everyone, As a specialist in obesity medicine and metabolic health, one of the most common questions I hear during the warmer months is: Can I stay on my GLP-1 medication and still enjoy the summer? The answer is: Absolutely, yes
However, Zepbound had a slightly lower discontinuation rate due to adverse effects
Cannabinoid receptor 1 (CB1R) is expressed in presynaptic and postsynaptic neuronal sites in the lateral habenula, where they modulate behavioral responses to stress exposure, such that CB1R blockade reduced anxiety-like behaviors [50] and also in GABAergic cells in the ventral tegmental area (VTA) and their stimulation increases firing of dopamine neurons, which modulate reward [51]
Semaglutide is currently being investigated in two large phase III clinical trial programs for treating obesity: the STEP program, which aims to obtain regulatory approval for semaglutide as an anti-obesity drug and is evaluating cardiovascular outcomes in 17,500 patients
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